Project 03 · Computational Biology
HelixForge
Invents new antimicrobial peptides and screens them for activity and toxicity, then proves the numbers with homology-disjoint evaluation that most published work skips.
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Twenty letters.
Every protein is written in an alphabet of twenty amino acids.
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A new peptide is written.
HelixForge generates new antimicrobial peptide sequences, letter by letter.
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It folds into a helix.
Many antimicrobial peptides coil into a helix: one face oily, one face charged.
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Screened twice.
Two classifiers score every candidate: one for activity against microbes, one for toxicity.
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Tested on strangers.
Homology-disjoint evaluation: test peptides have no close relatives in training, so the score can't be memorised.
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All in your browser.
The models run on your own device with ONNX Runtime Web and Transformers.js, at zero cost.
The details
Under the hood.
HelixForge invents new antimicrobial peptides and screens them for activity and toxicity, then proves the numbers mean something, using homology-disjoint evaluation that most published work skips. Everything runs in your browser at zero cost.
- Homology-disjoint evaluation
- Activity and toxicity scoring
- Runs in the browser at zero cost
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